Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
CIEMAS 3381, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Hassouneh, W, Zhulina, EB, Chilkoti, A, and Rubinstein, M. "Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles." Macromolecules 48.12 (June 11, 2015): 4183-4195. Full Text

Ghoorchian, A, Simon, JR, Bharti, B, Han, W, Zhao, X, Chilkoti, A, and Lõpez, GP. "Bioinspired reversibly cross-linked hydrogels comprising polypeptide micelles exhibit enhanced mechanical properties." Advanced Functional Materials 25.21 (June 1, 2015): 3122-3130. Full Text

Mastria, EM, Chen, M, McDaniel, JR, Li, X, Hyun, J, Dewhirst, MW, and Chilkoti, A. "Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma." Journal of controlled release : official journal of the Controlled Release Society 208 (June 2015): 52-58. Full Text

Ghoorchian, A, Simon, JR, Bharti, B, Han, W, Zhao, X, Chilkoti, A, and López, GP. "Bioinspired Reversibly Cross-linked Hydrogels Comprising Polypeptide Micelles Exhibit Enhanced Mechanical Properties." Advanced Functional Materials 25.21 (June 2015): 3122-3130. Full Text

Kimmerling, KA, Furman, BD, Mangiapani, DS, Moverman, MA, Sinclair, SM, Huebner, JL, Chilkoti, A, Kraus, VB, Setton, LA, Guilak, F, and Olson, SA. "Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis." European cells & materials 29 (January 31, 2015): 124-139.

Bellucci, JJ, Bhattacharyya, J, and Chilkoti, A. "A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteins." Angewandte Chemie (International ed. in English) 54.2 (January 2015): 441-445. Full Text

Liu, J, Liu, W, Weitzhandler, I, Bhattacharyya, J, Li, X, Wang, J, Qi, Y, Bhattacharjee, S, and Chilkoti, A. "Ring-opening polymerization of prodrugs: a versatile approach to prepare well-defined drug-loaded nanoparticles." Angewandte Chemie (International ed. in English) 54.3 (January 2015): 1002-1006. Full Text

McDaniel, JR, Weitzhandler, I, Prevost, S, Vargo, KB, Appavou, M-S, Hammer, DA, Gradzielski, M, and Chilkoti, A. "Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles." Nano letters 14.11 (November 2014): 6590-6598. Full Text

Hill, RT, Kozek, KM, Hucknall, A, Smith, DR, and Chilkoti, A. "Nanoparticle-Film Plasmon Ruler Interrogated with Transmission Visible Spectroscopy." ACS photonics 1.10 (October 2014): 974-984. Full Text

Li, NK, García Quiroz, F, Hall, CK, Chilkoti, A, and Yingling, YG. "Molecular description of the LCST behavior of an elastin-like polypeptide." Biomacromolecules 15.10 (October 2014): 3522-3530. Full Text

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