Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
1427 CIEMAS, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Quiroz, FG, and Chilkoti, A. "Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers." Nature materials 14.11 (November 2015): 1164-1171. Full Text

Abedini-Nassab, R, Joh, DY, Van Heest, MA, Yi, JS, Baker, C, Taherifard, Z, Margolis, DM, Garcia, JV, Chilkoti, A, Murdoch, DM, and Yellen, BB. "Characterizing the Switching Thresholds of Magnetophoretic Transistors." Advanced materials (Deerfield Beach, Fla.) 27.40 (October 2015): 6176-6180. Full Text Open Access Copy

Qi, Y, and Chilkoti, A. "Protein-polymer conjugation-moving beyond PEGylation." Current opinion in chemical biology 28 (October 2015): 181-193. (Review) Full Text

Garanger, E, MacEwan, SR, Sandre, O, Brûlet, A, Bataille, L, Chilkoti, A, and Lecommandoux, S. "Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core." Macromolecules 48.18 (September 22, 2015): 6617-6627. Full Text

Roberts, S, Dzuricky, M, and Chilkoti, A. "Elastin-like polypeptides as models of intrinsically disordered proteins." FEBS letters 589.19 Pt A (September 2015): 2477-2486. (Review) Full Text

Bhattacharyya, J, Bellucci, JJ, Weitzhandler, I, McDaniel, JR, Spasojevic, I, Li, X, Lin, C-C, Chi, J-TA, and Chilkoti, A. "A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models." Nature communications 6 (August 4, 2015): 7939-. Full Text

Han, W, MacEwan, SR, Chilkoti, A, and López, GP. "Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles." Nanoscale 7.28 (July 2015): 12038-12044. Full Text

Hassouneh, W, Zhulina, EB, Chilkoti, A, and Rubinstein, M. "Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles." Macromolecules 48.12 (June 11, 2015): 4183-4195. Full Text

Ghoorchian, A, Simon, JR, Bharti, B, Han, W, Zhao, X, Chilkoti, A, and Lõpez, GP. "Bioinspired reversibly cross-linked hydrogels comprising polypeptide micelles exhibit enhanced mechanical properties." Advanced Functional Materials 25.21 (June 1, 2015): 3122-3130. Full Text

Mastria, EM, Chen, M, McDaniel, JR, Li, X, Hyun, J, Dewhirst, MW, and Chilkoti, A. "Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma." Journal of controlled release : official journal of the Controlled Release Society 208 (June 2015): 52-58. Full Text

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