Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
CIEMAS 3381, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Qi, Y, Simakova, A, Ganson, NJ, Li, X, Luginbuhl, KM, Özer, I, Liu, W, Hershfield, MS, Matyjaszewski, K, and Chilkoti, A. "A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity." Nature biomedical engineering 1 (January 2016). Full Text

Bhattacharjee, S, Liu, W, Wang, W-H, Weitzhandler, I, Li, X, Qi, Y, Liu, J, Pang, Y, Hunt, DF, and Chilkoti, A. "Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation." Chembiochem : a European journal of chemical biology 16.17 (November 2015): 2451-2455. Full Text

Quiroz, FG, and Chilkoti, A. "Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers." Nature materials 14.11 (November 2015): 1164-1171. Full Text

Li, NK, Fuss, WH, Tang, L, Gu, R, Chilkoti, A, Zauscher, S, and Yingling, YG. "Prediction of solvent-induced morphological changes of polyelectrolyte diblock copolymer micelles." Soft matter 11.42 (November 2015): 8236-8245. Full Text

Abedini-Nassab, R, Joh, DY, Van Heest, MA, Yi, JS, Baker, C, Taherifard, Z, Margolis, DM, Garcia, JV, Chilkoti, A, Murdoch, DM, and Yellen, BB. "Characterizing the Switching Thresholds of Magnetophoretic Transistors." Advanced materials (Deerfield Beach, Fla.) 27.40 (October 2015): 6176-6180. Full Text Open Access Copy

Qi, Y, and Chilkoti, A. "Protein-polymer conjugation-moving beyond PEGylation." Current opinion in chemical biology 28 (October 2015): 181-193. (Review) Full Text

Garanger, E, MacEwan, SR, Sandre, O, Brûlet, A, Bataille, L, Chilkoti, A, and Lecommandoux, S. "Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core." Macromolecules 48.18 (September 22, 2015): 6617-6627. Full Text

Roberts, S, Dzuricky, M, and Chilkoti, A. "Elastin-like polypeptides as models of intrinsically disordered proteins." FEBS letters 589.19 Pt A (September 2015): 2477-2486. (Review) Full Text

Bhattacharyya, J, Bellucci, JJ, Weitzhandler, I, McDaniel, JR, Spasojevic, I, Li, X, Lin, C-C, Chi, J-TA, and Chilkoti, A. "A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models." Nature communications 6 (August 4, 2015): 7939-. Full Text

Han, W, MacEwan, SR, Chilkoti, A, and López, GP. "Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles." Nanoscale 7.28 (July 2015): 12038-12044. Full Text

Pages

Chilkoti, A. "Nanoparticle biosensors." March 2003.

Chilkoti, A, Ma, HW, Hyun, J, and Nath, N. "Passive and active nonfouling polymer grafts." March 2003.

Hoffman, AS, Stayton, PS, Bulmus, V, Chen, G, Chen, J, Cheung, C, Chilkoti, A, Ding, Z, Dong, L, Fong, R, Lackey, CA, Long, CJ, Miura, M, Morris, JE, Murthy, N, Nabeshima, Y, Park, TG, Press, OW, Shimoboji, T, Shoemaker, S, Yang, HJ, Monji, N, Nowinski, RC, Cole, CA, Priest, JH, Harris, JM, Nakamae, K, Nishino, T, and Miyata, T. "Really smart bioconjugates of smart polymers and receptor proteins." December 1, 2000. Full Text

Pages