Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
CIEMAS 3381, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Weinberger, A, Walter, V, MacEwan, SR, Schmatko, T, Muller, P, Schroder, AP, Chilkoti, A, and Marques, CM. "Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes." Scientific Reports 7 (March 6, 2017). Full Text

Gonzalez, MA, Simon, JR, Ghoorchian, A, Scholl, Z, Lin, S, Rubinstein, M, Marszalek, P, Chilkoti, A, López, GP, and Zhao, X. "Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins." Advanced materials (Deerfield Beach, Fla.) 29.10 (March 2017). Full Text

Bhattacharyya, J, Weitzhandler, I, Ho, SB, McDaniel, JR, Li, X, Tang, L, Liu, J, Dewhirst, M, and Chilkoti, A. "Encapsulating a Hydrophilic Chemotherapeutic into Rod-Like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves Its Efficacy." Advanced Functional Materials 27.12 (March 2017): 1605421-1605421. Full Text

Widder, K, MacEwan, SR, Garanger, E, Núñez, V, Lecommandoux, S, Chilkoti, A, and Hinderberger, D. "Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers." Soft matter 13.9 (March 2017): 1816-1822. Full Text

Ozer, I, and Chilkoti, A. "Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins." Bioconjugate chemistry 28.3 (March 2017): 713-723. (Review) Full Text

Joh, DY, McGuire, F, Abedini-Nassab, R, Andrews, JB, Achar, RK, Zimmers, Z, Mozhdehi, D, Blair, R, Albarghouthi, F, Oles, W, Richter, J, Fontes, CM, Hucknall, AM, Yellen, BB, Franklin, AD, and Chilkoti, A. "Poly(oligo(ethylene glycol) methyl ether methacrylate) Brushes on High-κ Metal Oxide Dielectric Surfaces for Bioelectrical Environments." ACS applied materials & interfaces 9.6 (February 2017): 5522-5529. Full Text

Wang, J, MacEwan, SR, and Chilkoti, A. "Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH." Nano letters 17.2 (February 2017): 1226-1232. (Letter) Full Text

MacEwan, SR, Weitzhandler, I, Hoffmann, I, Genzer, J, Gradzielski, M, and Chilkoti, A. "Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides." Biomacromolecules 18.2 (February 2017): 599-609. Full Text

Luginbuhl, KM, Schaal, JL, Umstead, B, Mastria, EM, Li, X, Banskota, S, Arnold, S, Feinglos, M, D'Alessio, D, and Chilkoti, A. "One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer." Nature biomedical engineering 1 (January 2017). Full Text

Banskota, S, Yousefpour, P, and Chilkoti, A. "Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds." Macromolecular bioscience 17.1 (January 2017). (Review) Full Text

Pages

Liu, W, McDaniel, JR, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, MR, and Chilkoti, A. "Abstract 4341: A novel injectable polymer liquid that self-assembles into radioactive “seeds” for brachytherapy." April 15, 2013. Full Text

Caudill, C, Bhattacharyya, J, and Chilkoti, A. "Delivery of paclitaxel with elastin-like polypeptides." April 7, 2013.

Sinclair, SM, Bhattacharyya, J, Little, D, Bowles, RD, Gooden, DM, Toone, EJ, Chilkoti, A, and Setton, LA. "PHARMACOKINETICS OF A THERMALLY RESPONSIVE CURCUMIN CONJUGATE FOR LOCAL ANTAGONISM OF NEUROINFLAMMATION IN DISC HERNIATION." April 2013.

Ferris, R, Hucknall, A, Kwon, BS, Chilkoti, A, and Zauscher, S. "Field-induced nanolithography for the patterning of non-fouling polymer brushes." March 25, 2012.

Fluegel, S, Kiefer, T, Heimann, N, Buehler, J, Fischer, K, McDaniel, J, Chilkoti, A, and Schmidt, M. "Conjugates of polypeptides and synthetic polymers with oligonucleotides: Stars, micelles and multiblockcopolymers." March 25, 2012.

Pages