Faculty Profiles

Andrew T. McPhail
Professor Emeritus of Chemistry
3236 French Family Science Cen, Durham, NC 27708-0346
(919) 660-1552
(919) 660-1605



Ph.D., University of Glasgow (Scotland) 1963

B.S., University of Glasgow (Scotland) 1959

Kelly, J, Wolin, R, Connolly, M, Afonso, A, James, L, Kirshmeier, P, Bishop, WR, and McPhail, AT. "Synthesis of isomeric 3-piperidinyl and 3-pyrrolidinyl benzo[5,6]cyclohepta[1,2-b]pyridines: Sulfonamido derivatives as inhibitors of Ras prenylation." BIOORGANIC & MEDICINAL CHEMISTRY 6.6 (June 1998): 673-686. Full Text

Draper, RW, Puar, MS, Vater, EJ, and McPhail, AT. "An unusual dienone-phenol rearrangement product formed during the synthesis of mometasone furoate (Sch 32088)." STEROIDS 63.3 (March 1998): 135-140. Full Text

McKittrick, BA, Ma, K, Huie, K, Yumibe, N, Davis, H, Clader, JW, Czarniecki, M, and McPhail, AT. "Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity." JOURNAL OF MEDICINAL CHEMISTRY 41.5 (February 26, 1998): 752-759. Full Text

Pirrung, MC, Lee, YR, Morehead, AT, and McPhail, AT. "Revised Relative and Absolute Stereochemistry of (+)-Purpurin." J Nat Prod 61.1 (January 23, 1998): 89-91. Full Text

Baldwin, SW, Young, BG, and McPhail, AT. "Preparation and evaluation of a cyclic acyl nitrone as a synthon for stereospecific α-amino acid synthesis." Tetrahedron Letters 39.38 (1998): 6819-6822.

Huang, L-J, Kuo, S-C, Perng, C-Y, Chao, Y-H, Wu, T-S, McPhail, AT, Mauger, A, Cheng, H-H, and Lee, K-H. "Synthesis and Cytotoxicity of Acetyl-4H,9H-naphtho[2,3-b]thiophene-4,9-diones." Biorg. Med. Chem. Lett. 8 (1998): 2763-2768. (Academic Article)

Bucholtz, EC, Wyrick, SD, Owens, CE, McPhail, AT, and Booth, RG. "1-phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene (H-2-PAT): Effect of stereochemistry on binding and function at brain histamine receptors." MEDICINAL CHEMISTRY RESEARCH 8.6 (1998): 322-332.

Bhattacharya, AK, Jain, DC, Sharma, RP, Roy, R, and McPhail, AT. "Boron trifluoride-acetic anhydride catalysed rearrangement of dihydroarteannuin B." TETRAHEDRON 53.44 (November 3, 1997): 14975-14990. Full Text