Faculty Profiles

Andrew T. McPhail
Professor Emeritus of Chemistry
3212 French Family Science Center, Durham, NC 27708-0346
(919) 660-1552
(919) 660-1605



Ph.D., University of Glasgow (Scotland) 1963

B.S., University of Glasgow (Scotland) 1959

Guan, J, Zhu, XK, Brossi, A, Tachibana, Y, Bastow, KF, Verdier-Pinard, P, Hamel, E, McPhail, AT, and Lee, KH. "Antitumor agents. 192. Antitubulin effect and cytotoxicity of C(7)-oxygenated allocolchicinoids." COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 64.2 (February 1999): 217-228. Full Text

Galal, AM, Ahmad, MS, El-Feraly, FS, and McPhail, AT. "New products from the reactions of artemisinin with ammonia and amines." J Nat Prod 62.1 (January 1999): 54-58. Full Text

Draper, RW, Hu, B, McPhail, AT, Puar, MS, Vater, EJ, and Weber, L. "Unusual Hyroxyl-γ-sultone Byproducts of Steroid 21-Methanesulfonylation. An Efficient Synthesis of Mometasone 17-Furoate (Sch 32088)." Tetrahedron 55 (1999): 3355-3364. (Academic Article)

Saksena, AK, Jao, E, Murphy, B, Schumacher, D, Chan, TM, Puar, MS, Jenkins, JK, Maloney, D, Cordero, M, Pramanik, BN, Bartner, P, Das, PR, McPhail, AT, Girijavallabhan, VM, and Ganguly, AK. "Structure elucidation of Sch 49088, a novel everninomicin antibiotic containing an unusual hydroxylamino-ether sugar, everhydroxylaminose." TETRAHEDRON LETTERS 39.46 (November 12, 1998): 8441-8444. Full Text

Afonso, A, Puar, MS, Kelly, J, and McPhail, AT. "Synthesis of a C-11 spirocyclopropyl derivative of 8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta-[1,2b]pyridine." TETRAHEDRON LETTERS 39.42 (October 15, 1998): 7657-7660. Full Text

Afonso, A, Kelly, J, Puar, MS, McCombie, S, and McPhail, AT. "Synthesis of a C-11 spiropiperidino derivative of 8-chloro-6,11-dihydro 5H-benzo[5,6]cyclohepta[1,2-b]pyridine." TETRAHEDRON LETTERS 39.42 (October 15, 1998): 7661-7664. Full Text

Kelly, J, Puar, MS, Afonso, A, and McPhail, AT. "Acid-Catalyzed Rearrangement of 5-Bromo-3-[1-allyl-2-(3,5-dimethoxyphenyl)ethyl]-2-cyanopyridine." J Org Chem 63.17 (August 21, 1998): 6039-6042.

Zbaida, S, Du, Y, Shannon, D, Laudicina, D, Thonoor, CM, Ng, K, Blumenkrantz, N, Patrick, JE, Cayen, MN, Friary, R, Seidl, V, Chan, TM, Pramanik, B, Spangler, M, and McPhail, AT. "In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)-one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites." BIOPHARMACEUTICS & DRUG DISPOSITION 19.5 (July 1998): 315-332. Full Text

Shi, Q, Chen, K, Chen, X, Brossi, A, Verdier-Pinard, P, Hamel, E, McPhail, AT, Tropsha, A, and Lee, KH. "Antitumor agents. 183. Syntheses, conformational analyses, and antitubulin activity of allothiocolchicinoids." JOURNAL OF ORGANIC CHEMISTRY 63.12 (June 12, 1998): 4018-4025. Full Text