Faculty Profiles

Andrew T. McPhail
Professor Emeritus of Chemistry
3212 French Family Science Center, Durham, NC 27708-0346
(919) 660-1552
(919) 660-1605



Ph.D., University of Glasgow (Scotland) 1963

B.S., University of Glasgow (Scotland) 1959

Hsieh, PW, Chang, FR, McPhail, AT, Lee, KH, and Wu, YC. "New cembranolide analogues from the formosan soft coral Sinularia flexibilis and their cytotoxicity." NATURAL PRODUCT RESEARCH 17.6 (December 2003): 409-418. Full Text

Reichard, GA, Stengone, C, Paliwal, S, Mergelsberg, I, Majmundar, S, Wang, C, Tiberi, R, McPhail, AT, Piwinski, JJ, and Shih, NY. "Asymmetric synthesis of 4,4-disubstituted-2-imidazoli-dinones: Potent NK1 antagonists." ORGANIC LETTERS 5.23 (November 13, 2003): 4249-4251. Full Text

McCormick, JL, Osterman, R, Chan, TM, Das, PR, Pramanik, BN, Ganguly, AK, Girijavallabhan, VM, McPhail, AT, and Saksena, AK. "A highly stereoselective approach to novel 2,2,4-trisubstituted pyrrolidines by halocylization: key intermediates towards syntheses of nitrogen analogs of Noxafil (R)." TETRAHEDRON LETTERS 44.43 (October 20, 2003): 7997-8000. Full Text

Saksena, AK, Girijavallabhan, VM, Puar, MS, Pramanik, BN, Das, PR, and McPhail, AT. "An unusual acetonide group migration." TETRAHEDRON LETTERS 44.38 (September 15, 2003): 7201-7204. Full Text

Ganguly, AK, Seah, N, Popov, V, Wang, CH, Kuang, R, Saksena, AK, Pramanik, BN, Chan, TM, and McPhail, AT. "Solution- and solid-phase synthesis of enantiomerically pure spiro oxindoles." TETRAHEDRON LETTERS 43.49 (December 2, 2002): 8981-8983. Full Text

Blythin, DJ, Chen, X, Piwinski, JJ, Shih, NY, Shue, HJ, Anthes, JC, and McPhail, AT. "Synthesis and NK1/NK2 binding activities of a series of diacyl-substituted 2-arylpiperazines." BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12.21 (November 4, 2002): 3161-3165. Full Text

Han, SQ, Hamel, E, Bastow, KF, McPhail, AT, Brossi, A, and Lee, KH. "Antitumor agents. Part 215: Antitubulin effects of cytotoxic B-ring modified allocolchicinoids." BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12.20 (October 21, 2002): 2851-2853. Full Text

Reichard, GA, Spitler, J, Mergelsberg, I, Miller, A, Wong, G, Raghavan, R, Jenkins, J, Gan, T, and McPhail, AT. "The asymmetric synthesis of (3R)-N-methyl-2-oxo-[1,4 '-bipiperidine]-3-acetamide in quantity." TETRAHEDRON-ASYMMETRY 13.9 (May 28, 2002): 939-943. Full Text

Venkatraman, S, Njoroge, FG, Girijavallabhan, VV, and McPhail, AT. "Application of ruthenium-induced macrocyclization for the construction of macrocyclic depsipeptides." JOURNAL OF ORGANIC CHEMISTRY 67.9 (May 3, 2002): 3152-3155. Full Text

Wu, JH, McPhail, AT, Bastow, KF, Shiraki, H, Ito, J, and Lee, KH. "Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus." TETRAHEDRON LETTERS 43.8 (February 18, 2002): 1391-1393. Full Text