Faculty Profiles

Amanda Hargrove
Assistant Professor of Chemistry
3219 French Science Center, Durham, NC 27708
(919) 660-1522
(919) 660-1605



NIH Postdoctoral Fellow, Chemistry, California Institute of Technology 2010 - 2013

Ph.D., University of Texas at Austin 2010

B.S., Trinity University 2004

Research Areas:
Synthesis, Biomolecular Structure and Function, Biological, Organic

Hargrove, AE, Raskatov, JA, Meier, JL, Montgomery, DC, and Dervan, PB. "Characterization and solubilization of pyrrole-imidazole polyamide aggregates." Journal of Medicinal Chemistry 55.11 (2012): 5425-5432. Full Text

Raskatov, JA, Hargrove, AE, So, AY, and Dervan, PB. "Pharmacokinetics of Py-Im polyamides depend on architecture: Cyclic versus linear." Journal of the American Chemical Society 134.18 (2012): 7995-7999. Full Text

Hargrove, AE, Nieto, S, Zhang, T, Sessler, JL, and Anslyn, EV. "Artificial receptors for the recognition of phosphorylated molecules." Chemical reviews 111.11 (November 2011): 6603-6782. (Review) Full Text

Hargrove, AE, Ellington, AD, Anslyn, EV, and Sessler, JL. "Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides." Bioconjugate chemistry 22.3 (March 2011): 388-396. Full Text

Hargrove, AE, Reyes, RN, Riddington, I, Anslyn, EV, and Sessler, JL. "Boronic acid porphyrin receptor for ginsenoside sensing." Organic letters 12.21 (November 2010): 4804-4807. Full Text

Hargrove, AE, Zhong, Z, Sessler, JL, and Anslyn, EV. "Algorithms for the determination of binding constants and enantiomeric excess in complex host : guest equilibria using optical measurements." New Journal of Chemistry 34.2 (2010): 348-348. Full Text

Collins, BE, Sorey, S, Hargrove, AE, Shabbir, SH, Lynch, VM, and Anslyn, EV. "Probing Intramolecular B−N Interactions in Ortho -Aminomethyl Arylboronic Acids." The Journal of Organic Chemistry 74.11 (June 5, 2009): 4055-4060. Full Text

Pikulski, M, Hargrove, A, Shabbir, SH, Anslyn, EV, and Brodbelt, JS. "Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap." Journal of the American Society for Mass Spectrometry 18.12 (December 2007): 2094-2106. Full Text

Spence, JD, Hargrove, AE, Crampton, HL, and Thomas, DW. "Porphyrenediynes: synthesis and cyclization of meso-enediynylporphyrins." Tetrahedron Letters 48.4 (January 2007): 725-728. Full Text

Sessler, JL, Lee, JT, Ou, Z, Köhler, T, Hargrove, AE, Cho, W-S, Lynch, V, and Kadish, KM. "Chemical and electrochemical oxidation of N -alkyl cyclo[n]pyrroles." Journal of Porphyrins and Phthalocyanines 10.12 (December 2006): 1329-1336. Full Text