Faculty Profiles

Amanda Elaine Hargrove
Assistant Professor in the Department of Chemistry
Office: 
3219 French Science Center, Durham, NC 27708
Phone: 
(919) 660-1522
Fax: 
(919) 660-1605

Overview

Education:

Nih Postdoctoral Fellow, Chemistry, California Institute of Technology 2010 - 2013

Ph.D., University of Texas at Austin 2010

B.S., Trinity University 2004

Research Areas:
Synthesis, Biomolecular Structure and Function, Biological, Organic

Eubanks, CS, Forte, JE, Kapral, GJ, and Hargrove, AE. "Small Molecule-Based Pattern Recognition To Classify RNA Structure." Journal of the American Chemical Society 139.1 (January 2017): 409-416. Full Text

McFadden, EJ, and Hargrove, AE. "Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin." Biochemistry 55.11 (March 2016): 1615-1630. (Review) Full Text

Hargrove, AE, Martinez, TF, Hare, AA, Kurmis, AA, Phillips, JW, Sud, S, Pienta, KJ, and Dervan, PB. "Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide." Ed. IU Agoulnik. PLOS ONE 10.11 (November 16, 2015): e0143161-e0143161. Full Text

Burg, JM, Link, JE, Morgan, BS, Heller, FJ, Hargrove, AE, and McCafferty, DG. "KDM1 class flavin-dependent protein lysine demethylases." Biopolymers 104.4 (July 2015): 213-246. (Review) Full Text

Morgan, BS, and Hargrove, AE. "Synthetic receptors for oligonucleotides and nucleic acids." Monographs in Supramolecular Chemistry 2015-January.14 (January 1, 2015): 253-325.

Nickols, NG, Szablowski, JO, Hargrove, AE, Li, BC, Raskatov, JA, and Dervan, PB. "Activity of a Py-Im polyamide targeted to the estrogen response element." Molecular Cancer Therapeutics 12.5 (2013): 675-684. Full Text

Raskatov, JA, Nickols, NG, Hargrove, AE, Marinov, GK, Wold, B, and Dervan, PB. "Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide." Proceedings of the National Academy of Sciences of the United States of America 109.40 (2012): 16041-16045. Full Text

Hargrove, AE, Raskatov, JA, Meier, JL, Montgomery, DC, and Dervan, PB. "Characterization and solubilization of pyrrole-imidazole polyamide aggregates." Journal of Medicinal Chemistry 55.11 (2012): 5425-5432. Full Text

Raskatov, JA, Hargrove, AE, So, AY, and Dervan, PB. "Pharmacokinetics of Py-Im polyamides depend on architecture: Cyclic versus linear." Journal of the American Chemical Society 134.18 (2012): 7995-7999. Full Text

Hargrove, AE, Nieto, S, Zhang, T, Sessler, JL, and Anslyn, EV. "Artificial receptors for the recognition of phosphorylated molecules." Chemical reviews 111.11 (November 2011): 6603-6782. (Review) Full Text

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