Faculty Profiles

Alvin L. Crumbliss
University Distinguished Service Professor Emeritus
Office: 
2104 French Family Science Center, Box 90346, Durham, NC 27708-0354
Phone: 
(919) 660-1540

Overview

Education:

Ph.D., Northwestern University 1968

B.A., Knox College 1964

Research Areas:
Biomolecular Structure and Function, Biological, Inorganic

Gebhardt, P, Crumbliss, AL, Miller, MJ, and Möllmann, U. "Synthesis and biological activity of saccharide based lipophilic siderophore mimetics as potential growth promoters for mycobacteria." Biometals 21.1 (February 2008): 41-51. Full Text

Weaver, KD, Heymann, JJ, Mehta, A, Roulhac, PL, Anderson, DS, Nowalk, AJ, Adhikari, P, Mietzner, TA, Fitzgerald, MC, and Crumbliss, AL. "Ga3+ as a mechanistic probe in Fe3+ transport: Characterization of Ga3+ interaction with FbpA." Journal of Biological Inorganic Chemistry 13.6 (2008): 887-898. Full Text

Dhungana, S, Harrington, JM, Gebhardt, P, Möllmann, U, and Crumbliss, AL. "Iron chelation equilibria, redox, and siderophore activity of a saccharide platform ferrichrome analogue." Inorg Chem 46.20 (October 1, 2007): 8362-8371. Full Text

Remington, N, Stevens, RD, Wells, RS, Holn, A, Dhungana, S, Taboy, CH, Crumbliss, AL, Henkens, R, and Bonaventura, C. "Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins." Gene 398.1-2 (August 15, 2007): 123-131. Full Text

Heymann, JJ, Weaver, KD, Mietzner, TA, and Crumbliss, AL. "Sulfate as a synergistic anion facilitating iron binding by the bacterial transferrin FbpA: the origins and effects of anion promiscuity." J Am Chem Soc 129.31 (August 8, 2007): 9704-9712. Full Text

Bonaventura, C, Henkens, R, Alayash, AI, and Crumbliss, AL. "Allosteric effects on oxidative and nitrosative reactions of cell-free hemoglobins." IUBMB Life 59.8-9 (August 2007): 498-505. (Review) Full Text

Anderson, DS, Adhikari, P, Weaver, KD, Crumbliss, AL, and Mietzner, TA. "The Haemophilus influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease and development of a gallium-based screen for mutants." J Bacteriol 189.14 (July 2007): 5130-5141. Full Text

Anderson, DS, Adhikari, P, Weaver, KD, Crumbliss, AL, and Mietzner, TA. "The Haemophilus influenzae hFbpABC Fe3+ Transporter: Analysis of the Membrane Permease and Development of a Mutational Screen Based on Resistance to Gallium." J. Bacteriology 189 (2007): 5130-. (Academic Article)

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