Faculty Profiles

Alvin L. Crumbliss
University Distinguished Service Professor Emeritus
Office: 
2104 French Family Science Center, Box 90346, Durham, NC 27708-0354
Phone: 
(919) 660-1540

Overview

Education:

Ph.D., Northwestern University 1968

B.A., Knox College 1964

Research Areas:
Biomolecular Structure and Function, Biological, Inorganic

Mollan, TL, Banerjee, S, Wu, G, Parker Siburt, CJ, Tsai, A-L, Olson, JS, Weiss, MJ, Crumbliss, AL, and Alayash, AI. "α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide." J Biol Chem 288.6 (February 8, 2013): 4288-4298. Full Text

Fago, A, Crumbliss, AL, Hendrich, MP, Pearce, LL, Peterson, J, Henkens, R, and Bonaventura, C. "Oxygen binding to partially nitrosylated hemoglobin." Biochimica et Biophysica Acta - Proteins and Proteomics 1834.9 (2013): 1894-1900. Full Text

Harrington, JM, Gootz, T, Flanagan, M, Lall, M, O'Donnell, J, Winton, J, Mueller, J, and Crumbliss, AL. "Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation." Biometals 25.5 (October 2012): 1023-1036. Full Text

Banerjee, S, Jia, Y, Siburt, CJP, Abraham, B, Wood, F, Bonaventura, C, Henkens, R, Crumbliss, AL, and Alayash, AI. "Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions." Free Radic Biol Med 53.6 (September 15, 2012): 1317-1326. Full Text

Harrington, JM, Boyd, WA, Smith, MV, Rice, JR, Freedman, JH, and Crumbliss, AL. "Amelioration of metal-induced toxicity in Caenorhabditis elegans: utility of chelating agents in the bioremediation of metals." Toxicol Sci 129.1 (September 2012): 49-56. Full Text

Banerjee, S, Siburt, CJP, Mistry, S, Noto, JM, DeArmond, P, Fitzgerald, MC, Lambert, LA, Cornelissen, CN, and Crumbliss, AL. "Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport." Metallomics 4.4 (April 2012): 361-372. Full Text

Parker Siburt, CJ, Mietzner, TA, and Crumbliss, AL. "FbpA--a bacterial transferrin with more to offer." Biochim Biophys Acta 1820.3 (March 2012): 379-392. (Review) Full Text

Tran, DT, Banerjee, S, Alayash, AI, Crumbliss, AL, and Fitzgerald, MC. "Slow histidine H/D exchange protocol for thermodynamic analysis of protein folding and stability using mass spectrometry." Anal Chem 84.3 (February 7, 2012): 1653-1660. Full Text

Crumbliss, AL, and Parker Siburt, CJ. "Iron Transport in Living Cells." (January 13, 2012): 483-549. (Chapter) Full Text

Kraiter, DC, Wisian-Neilson, P, Zhang, C, and Crumbliss, AL. "Synthesis and redox characterization of phosphazene terpolymers with pendant ferrocene groups." Macromolecules 45.9 (2012): 3658-3668. Full Text

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